URL: https://web.expasy.org/cellosaurus/CVCL_0549
Proper Citation: (CLS Cat# 604328, RRID:CVCL_0549)
Description: Cell line Sf9 is a Spontaneously immortalized cell line with a species of origin Spodoptera frugiperda
Sex: Female
Defining Citation: PMID:1367489, PMID:1369220, PMID:7615077, PMID:8050503, PMID:8314732, PMID:8799737, PMID:10718368, PMID:10777062, PMID:12052082, PMID:14668217, PMID:15926859, PMID:19003226, PMID:19941903, PMID:20300881, PMID:21667340, PMID:23891577, PMID:24375231, PMID:24672045, PMID:28423032, PMID:28839023, PMID:29038528, PMID:29133148
Comments: Derived from sampling site: Ovary., Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome.., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Omics: Genome sequenced., Omics: Transcriptome analysis., Omics: ESTs sequenced., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Doubling time: 25.2 +- 2.8 hours, at 28 Celsius (PubMed=10718368); 27 hours (PubMed=21667340); ~50 hours (DSMZ)., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank; DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line., Discontinued: RCB; RCB0563; true.
Category: Spontaneously immortalized cell line
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Discontinued
Discontinued: RCB; RCB0563
Source: Cellosaurus
